Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 4/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340091 | 0.83 | CCR2 (0.41) | ERN1WDR5RAD51CCR2ALDH1A1 | |
| SCHEMBL25979891 | 0.81 | HSD17B10 (0.49) | ERN1WDR5RAD51PTGS1ALDH1A1 | |
| SCHEMBL3275593 | 0.78 | PTGS1 (0.61) | PTGS1ALDH1A1LMNAHPGDHIF1A | |
| SCHEMBL10518952 | 0.77 | SMN1; SMN2 (0.55) | PTGS1ALDH1A1LMNAENPP2GAA | |
| SCHEMBL2641943 | 0.77 | TRPA1 (0.50) | PTGS1ALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL18254534 | 0.77 | L3MBTL1 (0.44) | RAD51CCR2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27892677 | 0.76 | RAD51 (0.37) | RAD51CCR2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10960303 | 0.75 | WDR5 (0.56) | ERN1WDR5HPGDMCL1 | |
| SCHEMBL22396701 | 0.75 | CA3 (0.41) | WDR5PTGS1CCR2 | |
| SCHEMBL7051361 | 0.75 | L3MBTL1 (0.57) | ALDH1A1HPGDHIF1AHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |