SCHEMBL8313839

SCHEMBL8313839

Nc1ccc(NNC(=O)C(F)F)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.45
RAB9A P51151 1/20 0.45
GAA P10253 6/20 0.43
LMNA P02545 5/20 0.41
TDP1 Q9NUW8 3/20 0.41
PKM P14618 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
ALDH1A1 P00352 2/20 0.39
PTGS1 P23219 2/20 0.38
KDM4E B2RXH2 2/20 0.38
GLA P06280 1/20 0.38
THRB P10828 1/20 0.38
BLM P54132 1/20 0.38
CASP6 P55212 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9188891 0.81 PTGS2 (0.51) MAPTGAALMNATDP1PKM
SCHEMBL9188482 0.80 GAA (0.66) MAPTGAALMNATDP1PKM
SCHEMBL8314482 0.75 ALDH1A1 (0.55) MAPTGAALMNATDP1PKM
SCHEMBL8861401 0.74 TSHR (0.63) MAPTRAB9AGAALMNATDP1
SCHEMBL8476433 0.73 MAPT (0.45) MAPTRAB9AGAALMNATDP1
SCHEMBL9191124 0.73 GAA (0.49) MAPTRAB9AGAALMNATDP1
SCHEMBL7143357 0.69 GAA (0.65) MAPTGAALMNATDP1PKM
SCHEMBL4422618 0.68 MAPT (0.57) MAPTRAB9ALMNATDP1PKM
Hydrochloric Acid SCHEMBL11695801 0.68 GAA (0.63) MAPTGAALMNATDP1PKM
SCHEMBL11142311 0.68 PTGS2 (0.75) MAPTRAB9AGAALMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0782042-B1 Hydrazine compound and silver halide photographic photosensitive material comprising the same FUJI PHOTO FILM CO LTD (JP) 1999-12-01 EP disclosed
EP-0782041-B1 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1999-11-17 EP disclosed
US-5789139-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1998-08-04 US disclosed
US-5770344-A AROMATIC HYDRAZIDE DERIVATIVE; HIGH CONTRAST; PROCESSING AND STORAGE STABILITY; GRAPHIC ARTS FUJI PHOTO FILM CO., LTD. (JP) 1998-06-23 US disclosed
EP-0782042-A2 Hydrazine compound and silver halide photographic photosensitive material comprising the same FUJI PHOTO FILM CO., LTD. (JP) 1997-07-02 EP disclosed
EP-0782041-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1997-07-02 EP disclosed