Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833337 | 1.00 | NPSR1 (0.34) | NPSR1ALDH1A1TDP1TSHRCHRM2 | |
| SCHEMBL8313398 | 0.84 | ALDH1A1 (0.42) | NPSR1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL4838497 | 0.84 | ALDH1A1 (0.42) | NPSR1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8313412 | 0.83 | ALDH1A1 (0.36) | NPSR1ALDH1A1TDP1TSHRCHRM2 | |
| SCHEMBL4845001 | 0.83 | ALDH1A1 (0.36) | NPSR1ALDH1A1TDP1TSHRCHRM2 | |
| SCHEMBL14254617 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4843406 | 0.83 | ALDH1A1 (0.37) | ALDH1A1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5792149 | 0.80 | MEN1 (0.36) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL4845496 | 0.80 | MEN1 (0.36) | ALDH1A1TDP1TSHRMEN1KMT2A | |
| SCHEMBL8312298 | 0.75 | PDE6D (0.37) | NPSR1ALDH1A1TDP1TSHRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342007-B2 | Lactams and uses thereof | ASTRAZENECA AB (SE) | 2008-03-11 | — | — | US | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |