Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 4/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8311899 | 0.99 | RAB9A (0.39) | RAB9ATSHRHSD17B10NPC1KDM4E | |
| SCHEMBL8314532 | 0.97 | RAB9A (0.40) | RAB9ATSHRHSD17B10NPC1KDM4E | |
| Hydrochloric Acid SCHEMBL8317512 | 0.96 | RAB9A (0.39) | RAB9ATSHRHSD17B10NPC1KDM4E | |
| Hydrochloric Acid SCHEMBL8313444 | 0.89 | ALDH1A1 (0.39) | RAB9ATSHRHSD17B10NPC1KDM4E | |
| Hydrochloric Acid SCHEMBL8315182 | 0.83 | PARP1 (0.37) | HSD17B10KDM4EALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL8317111 | 0.83 | BCHE (0.31) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL8315862 | 0.82 | ALOX5 (0.44) | RAB9AHSD17B10NPC1KDM4EALDH1A1 | |
| SCHEMBL8312064 | 0.81 | KDM4E (0.36) | TSHRHSD17B10KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8316051 | 0.81 | BCHE (0.31) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL8310477 | 0.79 | CYP11B1 (0.40) | TSHRHSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351856-B1 | Thiazolo[5,4-b]azepine compounds | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-09-15 | — | — | EP | disclosed |
| US-5300639-A | 2-oxo-3-carbonylamino-substituted azepine intermediates; lipoperoxide formation inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-04-05 | — | — | US | disclosed |