Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 4/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8317512 | 0.99 | RAB9A (0.39) | RAB9ATSHRHSD17B10ALDH1A1NPC1 | |
| SCHEMBL8314378 | 0.97 | RAB9A (0.40) | RAB9ATSHRHSD17B10ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL8311899 | 0.96 | RAB9A (0.39) | RAB9ATSHRHSD17B10ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL8313444 | 0.86 | ALDH1A1 (0.39) | RAB9ATSHRHSD17B10ALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL8315182 | 0.81 | PARP1 (0.37) | HSD17B10ALDH1A1KDM4EMAPTHPGD | |
| Hydrochloric Acid SCHEMBL8317111 | 0.81 | BCHE (0.31) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL8315862 | 0.80 | ALOX5 (0.44) | RAB9AHSD17B10ALDH1A1NPC1KDM4E | |
| SCHEMBL8312064 | 0.79 | KDM4E (0.36) | TSHRHSD17B10ALDH1A1KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8316051 | 0.78 | BCHE (0.31) | ACHEBCHEGRIN1GRIN2A | |
| SCHEMBL8310477 | 0.77 | CYP11B1 (0.40) | TSHRHSD17B10ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443588-B1 | Condensed thiazole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-23 | — | — | EP | claimed |
| US-5153201-A | Inhibitors of lipoperoxide and lipoxygenase; antiischemic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | claimed |
| EP-0443588-A1 | Condensed thiazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-28 | — | — | EP | claimed |
| EP-0679642-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-11-10 | — | — | EP | disclosed |
| EP-0443588-B1 | Condensed thiazole compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5654296-A | HORMONE INHIBITOR; NERVOUS SYSTEM DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-05 | — | — | US | disclosed |
| US-5607939-A | CALCIUM ANTAGONIST, GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONIST AND MONOAMINEU UPTAKE INHIBITORS FOR CENTRAL NERVOUS SYSTEM DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0679642-A1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-11-02 | — | — | EP | disclosed |
| US-5153201-A | Inhibitors of lipoperoxide and lipoxygenase; antiischemic agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0443588-A1 | Condensed thiazole compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-08-28 | — | — | EP | disclosed |