Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311773 | 0.82 | NPC1 (0.50) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL3393276 | 0.79 | SLC27A1 (0.74) | SLC27A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17287636 | 0.76 | CSNK1D (0.80) | SLC27A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL6864740 | 0.75 | SLC27A1 (0.67) | SLC27A1SMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL5327560 | 0.75 | SLC27A1 (0.66) | SLC27A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL11255823 | 0.73 | HPGD (0.55) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL27909367 | 0.73 | SLC27A1 (0.61) | SLC27A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7522067 | 0.73 | SLC27A1 (0.84) | SLC27A1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL4806814 | 0.73 | SLC27A1 (0.63) | SLC27A1MEN1KMT2A | |
| SCHEMBL8358629 | 0.73 | SLC27A1 (0.63) | SLC27A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929550-A1 | $i(N)-(BENZOTHIAZOL-2-YL) PIPERIDINE-1-ETHANAMINE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014444-A1 | N-(BENZOTHIAZOL-2-YL) PIPERIDINE-1-ETHANAMINE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1998-04-09 | — | — | WO | disclosed |