Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 6/20 | 0.42 |
| ▸ | PRKCA | P17252 | 6/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317078 | 0.89 | CAMK2D (0.48) | PRKCBPRKCACAMK2DKLK1PRKCD | |
| Hydrochloric Acid SCHEMBL8318720 | 0.88 | CAMK2D (0.48) | PRKCBPRKCACAMK2DKLK1PRKCD | |
| Hydrochloric Acid SCHEMBL8316493 | 0.85 | CAMK2D (0.42) | PRKCBPRKCACAMK2DMAPTMEN1 | |
| SCHEMBL8319658 | 0.84 | ROCK2 (0.45) | PRKCBPRKCACAMK2DKDM4EALDH1A1 | |
| SCHEMBL8317092 | 0.84 | ROCK2 (0.45) | PRKCBPRKCACAMK2DKDM4EALDH1A1 | |
| SCHEMBL8316483 | 0.84 | CAMK2D (0.51) | PRKCBPRKCACAMK2DKLK1PRKCD | |
| Hydrochloric Acid SCHEMBL8319262 | 0.83 | ROCK2 (0.44) | PRKCBPRKCACAMK2DKDM4EALDH1A1 | |
| SCHEMBL8314832 | 0.80 | CAMK2D (0.43) | PRKCBPRKCACAMK2DPRKCDPRKCH | |
| SCHEMBL8318394 | 0.80 | HTR6 (0.42) | KDM4EALDH1A1MAPTMEN1HPGD | |
| Hydrochloric Acid SCHEMBL8317707 | 0.80 | CAMK2D (0.42) | PRKCBPRKCACAMK2DPRKCDPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925296-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1999-06-30 | — | — | EP | claimed |
| WO-1998011102-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | claimed |
| EP-0925296-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011102-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | disclosed |