Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9030544 | 0.92 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL8315697 | 0.91 | PDE4D (0.40) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL8319261 | 0.87 | TBXAS1 (0.41) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL8319280 | 0.87 | PDE4D (0.36) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL7680850 | 0.86 | TP53 (0.43) | TP53GPR119KDM4EPKM | |
| SCHEMBL8318596 | 0.86 | GPR119 (0.39) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL8319314 | 0.81 | PDE4D (0.41) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL9031543 | 0.78 | TP53 (0.46) | TP53GPR119USP2KDM4EPKM | |
| SCHEMBL8318274 | 0.78 | TBXAS1 (0.42) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL8318295 | 0.78 | PDE4D (0.36) | PDE4DPDE4APDE4BPDE4CTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |