Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8318295 | 0.92 | PDE4D (0.36) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL8316433 | 0.89 | ITGB3 (0.37) | PDE4BKDM4EMAPT | |
| SCHEMBL8315355 | 0.87 | PDE4D (0.40) | PDE4DPDE4APDE4BPDE4CTP53 | |
| Trifluoroacetic Acid SCHEMBL8317333 | 0.86 | ITGB3 (0.36) | — | |
| SCHEMBL9030544 | 0.85 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL8315697 | 0.84 | PDE4D (0.40) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL8319261 | 0.84 | TBXAS1 (0.41) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL8318596 | 0.82 | GPR119 (0.39) | PDE4DPDE4APDE4BPDE4CTP53 | |
| SCHEMBL7680850 | 0.80 | TP53 (0.43) | TP53GPR119KDM4E | |
| SCHEMBL8317905 | 0.79 | ITGB3 (0.38) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |