Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319204 | 0.88 | ITGB3 (0.35) | — | |
| SCHEMBL8315697 | 0.86 | PDE4D (0.40) | GPR119PDE4DPDE4APDE4BPDE4C | |
| Trifluoroacetic Acid SCHEMBL8318415 | 0.86 | ITGB3 (0.34) | — | |
| SCHEMBL8315355 | 0.86 | PDE4D (0.40) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9030544 | 0.84 | PDE4D (0.44) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8319261 | 0.84 | TBXAS1 (0.41) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8319280 | 0.82 | PDE4D (0.36) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7680850 | 0.80 | TP53 (0.43) | GPR119TP53 | |
| SCHEMBL8319314 | 0.77 | PDE4D (0.41) | GPR119PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8318274 | 0.75 | TBXAS1 (0.42) | GPR119PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |