Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.45 |
| ▸ | EBP | Q15125 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317854 | 0.94 | CYP2D6 (0.46) | MEN1KMT2AEBPSIGMAR1TMEM97 | |
| SCHEMBL8316856 | 0.86 | OPRM1 (0.52) | OPRM1OPRD1OPRK1SETD7SIGMAR1 | |
| SCHEMBL8312626 | 0.85 | DRD4 (0.47) | OPRM1OPRD1OPRK1KMT2ASETD7 | |
| SCHEMBL9253379 | 0.84 | SETD7 (0.57) | OPRM1OPRD1OPRK1SETD7DRD2 | |
| SCHEMBL27508978 | 0.84 | OPRM1 (0.45) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL10559361 | 0.83 | KMT2A (0.57) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL7441629 | 0.82 | KDM4E (0.49) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL8314872 | 0.82 | OPRD1 (0.55) | OPRM1OPRD1OPRK1SETD7P2RX7 | |
| SCHEMBL8317597 | 0.81 | OPRM1 (0.49) | OPRM1OPRD1OPRK1SETD7DRD4 | |
| SCHEMBL8317082 | 0.81 | OPRD1 (0.49) | OPRM1OPRD1OPRK1SETD7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |