Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314872 | 0.88 | OPRD1 (0.55) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL9253379 | 0.88 | SETD7 (0.57) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8314768 | 0.86 | OPRM1 (0.47) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8312626 | 0.84 | DRD4 (0.47) | OPRD1OPRM1OPRK1SETD7KDM4E | |
| SCHEMBL8315004 | 0.83 | OPRD1 (0.47) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8317597 | 0.82 | OPRM1 (0.49) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8316876 | 0.82 | OPRD1 (0.53) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8315369 | 0.82 | MEN1 (0.44) | OPRD1OPRM1OPRK1P2RX7KCNH2 | |
| SCHEMBL8315432 | 0.81 | OPRM1 (0.48) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8316991 | 0.81 | OPRM1 (0.52) | OPRD1OPRM1OPRK1SETD7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |