Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314793 | 0.84 | HRH3 (0.55) | ALDH1A1CHRM2KMT2AMEN1 | |
| SCHEMBL8313001 | 0.84 | MEN1 (0.45) | ALDH1A1TSHRMMP1MMP9MMP13 | |
| SCHEMBL8314512 | 0.81 | CHRM2 (0.47) | ALDH1A1LMNAKDM4EMMP1MMP9 | |
| SCHEMBL7353607 | 0.79 | S1PR5 (0.58) | ALDH1A1LMNAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL9646910 | 0.79 | PKM (0.68) | POLBMAPK1NSD2GAAGFER | |
| SCHEMBL8313087 | 0.78 | CHRM2 (0.54) | ALDH1A1LMNAPOLBGAACHRM2 | |
| SCHEMBL8313105 | 0.77 | HDAC3 (0.52) | KMT2AMEN1 | |
| SCHEMBL7347681 | 0.76 | ALDH1A1 (0.64) | ALDH1A1LMNAPOLBSMN1; SMN2KDM4E | |
| SCHEMBL28213371 | 0.73 | SIGMAR1 (0.55) | ALDH1A1LMNAPOLBMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28859867 | 0.72 | SIGMAR1 (0.54) | ALDH1A1LMNAPOLBMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004066960-A2 | COMBINATION OF H1, H3 AND H4 RECEPTOR ANTAGONISTS FOR TREATMENT OF ALLERGIC AND NON-ALLERGIC PULMONARY INFLAMMATION, CONGESTION AND ALLERGIC RHINITIS | SCHERING CORPORATION (US) | 2004-08-12 | — | — | WO | disclosed |