Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315477 | 0.81 | ALDH1A1 (0.51) | CHRM2ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL8314793 | 0.80 | HRH3 (0.55) | CHRM2ALDH1A1KMT2AMEN1CYP2D6 | |
| SCHEMBL8313001 | 0.79 | MEN1 (0.45) | CHRM2ALDH1A1KMT2AMEN1CYP2D6 | |
| SCHEMBL8313087 | 0.77 | CHRM2 (0.54) | CHRM2CHRM1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8314516 | 0.75 | CHRM2 (0.52) | CHRM2CHRM1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8313105 | 0.72 | HDAC3 (0.52) | KMT2AMEN1 | |
| SCHEMBL8314558 | 0.72 | CHRM2 (0.55) | CHRM2 | |
| SCHEMBL8319668 | 0.71 | CHRM2 (0.52) | CHRM2CHRM1S1PR5CHRM4HRH3 | |
| SCHEMBL31277295 | 0.71 | MAPK1 (0.51) | ALDH1A1KMT2AKDM4EMEN1CYP2D6 | |
| SCHEMBL1006676 | 0.70 | SMN1; SMN2 (0.45) | KMT2AMEN1CHRM4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004066960-A2 | COMBINATION OF H1, H3 AND H4 RECEPTOR ANTAGONISTS FOR TREATMENT OF ALLERGIC AND NON-ALLERGIC PULMONARY INFLAMMATION, CONGESTION AND ALLERGIC RHINITIS | SCHERING CORPORATION (US) | 2004-08-12 | — | — | WO | disclosed |