Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315782 | 0.88 | CA12 (0.35) | OPRL1OPRM1 | |
| SCHEMBL8316858 | 0.74 | ELANE (0.39) | KDM4EALDH1A1HSD17B10TDP1 | |
| SCHEMBL8317764 | 0.69 | CA12 (0.38) | OPRM1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7332181 | 0.66 | KMT2A (0.45) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8314617 | 0.64 | LMNA (0.37) | — | |
| SCHEMBL8311345 | 0.63 | OPRL1 (0.43) | OPRL1OPRM1 | |
| SCHEMBL18597095 | 0.61 | HTR5A (0.32) | — | |
| SCHEMBL21408666 | 0.60 | CRHBP (0.31) | — | |
| SCHEMBL7335334 | 0.60 | — | — | |
| SCHEMBL22132286 | 0.58 | GAA (0.37) | OPRM1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929072-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |
| EP-0897921-A1 | Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands | ELI LILLY AND COMPANY LIMITED (GB) | 1999-02-24 | — | — | EP | disclosed |