Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684807 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL3616609 | 0.79 | KDM4E (0.54) | ALDH1A1HPGDPOLBSMN1; SMN2CYP1A2 | |
| SCHEMBL8311007 | 0.77 | ALDH1A1 (0.37) | ALDH1A1HPGDSMN1; SMN2CYP1A2CA2 | |
| SCHEMBL1511820 | 0.74 | KDM4E (0.51) | ALDH1A1HPGDPOLBSMN1; SMN2CA2 | |
| SCHEMBL10373029 | 0.73 | CYP2A6 (0.45) | ALDH1A1HPGDPOLBSMN1; SMN2CYP1A2 | |
| SCHEMBL14060422 | 0.69 | KDM4E (0.59) | ALDH1A1HPGDRAD52CYP1A2CYP2A6 | |
| SCHEMBL347082 | 0.69 | SLC2A1 (0.43) | ALDH1A1HPGDCYP1A2CYP2A6CA2 | |
| SCHEMBL11464784 | 0.69 | NR4A2 (0.51) | ALDH1A1HPGDPOLBSMN1; SMN2CA2 | |
| SCHEMBL10962305 | 0.69 | ADRA1A (0.50) | ALDH1A1HPGDCYP1A2KDM4ETSHR | |
| SCHEMBL11683585 | 0.68 | MAOB (0.58) | ALDH1A1SMN1; SMN2APPMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |