Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 6/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.43 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.43 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948650 | 0.76 | SIGMAR1 (0.41) | GRM2F10 | |
| SCHEMBL15221195 | 0.76 | F10 (0.65) | F10 | |
| SCHEMBL7298956 | 0.76 | GRM2 (0.69) | GRM2F10 | |
| SCHEMBL8948654 | 0.75 | RECQL (0.36) | GRM2F10TNKSTNKS2 | |
| SCHEMBL592344 | 0.73 | CHRM2 (0.46) | GRM2F10 | |
| SCHEMBL592809 | 0.73 | POLB (0.43) | GRM2F10 | |
| Benzyl Benzylcarbamate SCHEMBL1136818 | 0.73 | PLAU (0.70) | PLAUTNKSTNKS2HDAC3HDAC1 | |
| SCHEMBL28584298 | 0.72 | PLAU (0.54) | PLAUTNKSTNKS2HDAC3HDAC1 | |
| SCHEMBL7314568 | 0.72 | F10 (0.48) | GRM2F10 | |
| Benzyl Benzylcarbamate SCHEMBL19810513 | 0.71 | PLAU (0.68) | PLAUTNKSTNKS2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623615-B1 | Substituted 1-phenyl-oxazolidin-2-one derivatives, their preparation and their use as adhesion-receptor antagonists | MERCK PATENT GMBH (DE) | 1999-06-30 | — | — | EP | disclosed |
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |
| EP-0623615-A1 | Adhesion-receptor antagonists | MERCK PATENT GmbH (DE) | 1994-11-09 | — | — | EP | disclosed |