Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8948693 | 0.83 | SIGMAR1 (0.43) | SIGMAR1ITGB3ITGA2B | |
| SCHEMBL8948654 | 0.81 | RECQL (0.36) | SIGMAR1ITGB3ITGA2BAURKAFLT1 | |
| SCHEMBL7310242 | 0.80 | ITGB3 (0.41) | SIGMAR1ITGB3ITGA2BF10PARP1 | |
| SCHEMBL8948795 | 0.79 | GRM2 (0.46) | SIGMAR1ITGB3ITGA2BGRM2 | |
| SCHEMBL8948876 | 0.78 | SIGMAR1 (0.43) | SIGMAR1ITGB3ITGA2BGRM2 | |
| SCHEMBL8892115 | 0.77 | NAMPT (0.37) | F10MEN1KMT2A | |
| SCHEMBL8315856 | 0.76 | GRM2 (0.48) | F10GRM2 | |
| SCHEMBL6601341 | 0.75 | ITGB3 (0.43) | SIGMAR1ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL8315960 | 0.74 | ITGB3 (0.43) | SIGMAR1ITGB3ITGA2BF10PRSS1 | |
| SCHEMBL7462288 | 0.73 | LMNA (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | disclosed |