Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.53 |
| ▸ | CDK4 | P11802 | 4/20 | 0.47 |
| ▸ | CCND1 | P24385 | 4/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316860 | 0.88 | NQO1 (0.70) | NQO1CDK4CCND1CCNE2CCNE1 | |
| SCHEMBL8316997 | 0.77 | SIRT2 (0.53) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL8313203 | 0.70 | NQO1 (1.00) | NQO1CDK4CCND1CCNE2CCNE1 | |
| SCHEMBL8317087 | 0.70 | ATM (0.58) | ATMSMN1; SMN2CA9CA12CA1 | |
| SCHEMBL18669003 | 0.70 | CA9 (0.61) | ATMSMN1; SMN2CA9CA12CA1 | |
| SCHEMBL14708720 | 0.69 | NQO1 (0.64) | NQO1CDK4CCND1CCNE2CCNE1 | |
| SCHEMBL8318378 | 0.67 | NQO1 (0.68) | NQO1CDK4CCND1CCNE2CCNE1 | |
| SCHEMBL8195354 | 0.67 | CDK4 (0.86) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL5769090 | 0.66 | KCNN4 (0.51) | ATMSMN1; SMN2CA9CA12CA1 | |
| SCHEMBL11099626 | 0.66 | SMN1; SMN2 (0.58) | ATMSMN1; SMN2CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | claimed |