Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313203 | 0.82 | NQO1 (1.00) | NQO1ALDH1A1HPGDHTTPRKCA | |
| SCHEMBL8316860 | 0.79 | NQO1 (0.70) | NQO1HTTPRKCALMNACA12 | |
| SCHEMBL8316640 | 0.76 | SIRT2 (0.68) | ALDH1A1HPGDHTTLMNACA12 | |
| SCHEMBL2049541 | 0.75 | ALDH1A1 (0.73) | ALDH1A1HPGDHTTCA12CA2 | |
| SCHEMBL31687464 | 0.75 | ALDH1A1 (0.73) | ALDH1A1HPGDHTTCA12CA2 | |
| SCHEMBL8324352 | 0.74 | NQO1 (0.74) | NQO1PRKCAKMT2AMEN1PRKD3 | |
| SCHEMBL13431714 | 0.72 | NQO1 (0.73) | NQO1ALDH1A1HTTPRKCASMN1; SMN2 | |
| SCHEMBL9646860 | 0.72 | ALOX5 (0.54) | ALDH1A1HPGDHTTLMNAKMT2A | |
| SCHEMBL10341832 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HPGDHTTCA12CA2 | |
| SCHEMBL9623177 | 0.70 | NQO1 (0.71) | NQO1ALDH1A1HPGDHTTPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | claimed |