Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.70 |
| ▸ | CDK4 | P11802 | 3/20 | 0.55 |
| ▸ | CCND1 | P24385 | 3/20 | 0.55 |
| ▸ | PRKCA | P17252 | 3/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315890 | 0.88 | NQO1 (0.53) | NQO1CDK4CCND1TACR1CA9 | |
| SCHEMBL8313203 | 0.83 | NQO1 (1.00) | NQO1CDK4CCND1PRKCASMN1; SMN2 | |
| SCHEMBL14708720 | 0.81 | NQO1 (0.64) | NQO1CDK4CCND1PRKCACA9 | |
| SCHEMBL8318378 | 0.79 | NQO1 (0.68) | NQO1CDK4CCND1PRKCACA9 | |
| SCHEMBL8319736 | 0.79 | CDK4 (0.47) | NQO1CDK4CCND1PRKCASMN1; SMN2 | |
| SCHEMBL15959915 | 0.76 | NQO1 (0.58) | NQO1CDK4CCND1PRKCACA9 | |
| SCHEMBL18669003 | 0.75 | CA9 (0.61) | CA9ATMCA12SMN1; SMN2MAPT | |
| SCHEMBL8324352 | 0.73 | NQO1 (0.74) | NQO1CDK4CCND1PRKCAMAPT | |
| SCHEMBL8317087 | 0.72 | ATM (0.58) | CA9ATMCA12SMN1; SMN2MAPT | |
| SCHEMBL14708729 | 0.72 | NQO1 (0.49) | NQO1CDK4CCND1PRKCAPARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630242-B1 | FURTHER INDOLE DERIVATIVES WITH ANTIVIRAL ACTIVITY | WELLCOME FOUND (GB) | 1999-01-20 | — | — | EP | claimed |