Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314114 | 0.84 | HRH1 (0.50) | CYP2J2KCNH2MEN1SLC6A2SLC6A4 | |
| SCHEMBL8317345 | 0.80 | KCNH2 (0.54) | PAX8CYP2J2KCNH2MEN1SLC6A2 | |
| SCHEMBL8311543 | 0.80 | PAX8 (0.46) | PAX8CYP2J2KCNH2MEN1SLC6A2 | |
| SCHEMBL8316153 | 0.78 | CYP2J2 (0.60) | PAX8CYP2J2KCNH2MEN1KMT2A | |
| SCHEMBL16291199 | 0.78 | KCNH2 (0.67) | CYP2J2KCNH2MEN1SLC6A2SLC6A4 | |
| SCHEMBL10557081 | 0.74 | PAX8 (0.60) | PAX8CYP2J2KCNH2MEN1HRH1 | |
| SCHEMBL8315418 | 0.74 | PAX8 (0.40) | PAX8CYP2J2KCNH2SLC6A2SLC6A4 | |
| SCHEMBL11832136 | 0.74 | CYP2J2 (0.79) | CYP2J2KCNH2SLC6A2SLC6A4CHRM2 | |
| SCHEMBL7439663 | 0.73 | KCNH2 (0.51) | CYP2J2KCNH2MEN1SLC6A2SLC6A4 | |
| SCHEMBL8317518 | 0.72 | HRH1 (0.58) | CYP2J2KCNH2MEN1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |