Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2J2 | P51589 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 6/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317345 | 0.86 | KCNH2 (0.54) | CYP2J2KCNH2MEN1KMT2AHRH1 | |
| SCHEMBL16291199 | 0.86 | KCNH2 (0.67) | CYP2J2KCNH2MEN1KMT2AHRH1 | |
| SCHEMBL8316749 | 0.85 | HRH1 (0.63) | CYP2J2KCNH2MEN1KMT2AHRH1 | |
| SCHEMBL9504605 | 0.82 | HRH1 (0.64) | HRH1 | |
| SCHEMBL9504518 | 0.82 | SIGMAR1 (0.64) | CYP2J2KCNH2HRH1NPY2R | |
| Hydrochloric Acid SCHEMBL9787492 | 0.81 | SIGMAR1 (0.62) | CYP2J2KCNH2HRH1NPY2R | |
| SCHEMBL10460762 | 0.80 | KCNH2 (0.86) | CYP2J2KCNH2MEN1KMT2AHRH1 | |
| SCHEMBL8317518 | 0.80 | HRH1 (0.58) | CYP2J2KCNH2MEN1KMT2AHRH1 | |
| SCHEMBL8311543 | 0.80 | PAX8 (0.46) | CYP2J2KCNH2MEN1KMT2AHRH1 | |
| SCHEMBL10459146 | 0.79 | KCNH2 (0.56) | CYP2J2KCNH2MEN1KMT2APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |