Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.31 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795892 | 0.87 | EGFR (0.34) | EGFRMAPTKDM4EMAPK1TDP1 | |
| SCHEMBL8795889 | 0.87 | EGFR (0.34) | EGFRMAPTKDM4EMAPK1TDP1 | |
| SCHEMBL8313666 | 0.83 | TBXA2R (0.31) | EGFRMAPTKDM4EAKR1B1ALDH1A1 | |
| SCHEMBL8794786 | 0.82 | MEN1 (0.35) | EGFRMAPTMAPK1AKR1B1ALDH1A1 | |
| SCHEMBL8794789 | 0.82 | MEN1 (0.35) | EGFRMAPTMAPK1AKR1B1ALDH1A1 | |
| SCHEMBL8316094 | 0.81 | TLR3 (0.35) | EGFRMAPTAKR1B1ALDH1A1 | |
| SCHEMBL8311296 | 0.78 | AKR1B1 (0.37) | MAPTKDM4ETDP1AKR1B1ALDH1A1 | |
| SCHEMBL6270429 | 0.78 | AKR1B1 (0.40) | MAPTTDP1AKR1B1ALDH1A1CA1 | |
| SCHEMBL8312387 | 0.77 | ALDH1A1 (0.37) | MAPTTDP1AKR1B1ALDH1A1CTSL | |
| SCHEMBL8134324 | 0.77 | KMT2A (0.38) | MAPTKDM4ETDP1AKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |