Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | CCKBR | P32239 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795889 | 0.85 | EGFR (0.34) | TBXA2REGFRNR3C1AKR1B1KMT2A | |
| SCHEMBL8795892 | 0.85 | EGFR (0.34) | TBXA2REGFRNR3C1AKR1B1KMT2A | |
| SCHEMBL8316173 | 0.83 | EGFR (0.34) | EGFRAKR1B1ALDH1A1KDM4EMAPT | |
| SCHEMBL8315152 | 0.82 | EGFR (0.30) | EGFRAKR1B1KMT2AALDH1A1MEN1 | |
| SCHEMBL8794786 | 0.80 | MEN1 (0.35) | EGFRNR3C1AKR1B1KMT2AALDH1A1 | |
| SCHEMBL8794789 | 0.80 | MEN1 (0.35) | EGFRNR3C1AKR1B1KMT2AALDH1A1 | |
| SCHEMBL8316094 | 0.79 | TLR3 (0.35) | EGFRAKR1B1KMT2AALDH1A1MEN1 | |
| SCHEMBL8314877 | 0.79 | MEN1 (0.36) | ADORA3AKR1B1KMT2AALDH1A1MEN1 | |
| SCHEMBL8312522 | 0.78 | ALDH1A1 (0.36) | AKR1B1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8316461 | 0.77 | L3MBTL1 (0.41) | NR3C1AKR1B1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |