Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CTSV | O60911 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316089 | 0.97 | MAPKAPK2 (0.55) | MAPKAPK2MAOBMAOATDP1CTSV | |
| SCHEMBL25634129 | 0.87 | MCHR1 (0.61) | MAPKAPK2MAOBMAOACTSVCTSL | |
| SCHEMBL31153237 | 0.87 | MCHR1 (0.61) | MAPKAPK2MAOBMAOACTSVCTSL | |
| SCHEMBL25634296 | 0.84 | HRH3 (0.58) | MAPKAPK2MAOBMAOAMAPTTRPM8 | |
| SCHEMBL31153243 | 0.84 | HRH3 (0.58) | MAPKAPK2MAOBMAOAMAPTTRPM8 | |
| SCHEMBL2978779 | 0.84 | LMNA (0.63) | MAPKAPK2MAOBMAOACTSVCTSL | |
| SCHEMBL9672176 | 0.83 | MAOB (0.55) | MAPKAPK2MAOBMAOATDP1CTSV | |
| SCHEMBL7657783 | 0.81 | EGFR (0.67) | MAPKAPK2MAOBMAOACTSVCTSL | |
| Hydrochloric Acid SCHEMBL8606288 | 0.78 | EGFR (0.51) | MAPKAPK2ADRA1A | |
| SCHEMBL7143900 | 0.78 | ADRA1A (0.49) | MAPKAPK2MAOBMAOACTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690050-B1 | (Thia)cycloalkyl(b) indole derivatives as 5-lipoxygenase inhibitors | ADIR (FR) | 1999-11-17 | — | — | EP | claimed |
| EP-0690050-B1 | (Thia)cycloalkyl(b) indole derivatives as 5-lipoxygenase inhibitors | ADIR (FR) | 1999-11-17 | — | — | EP | disclosed |