Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630703 | 0.84 | SLC6A3 (0.45) | SLC6A3MEN1KMT2AKDM4CSLC6A2 | |
| SCHEMBL4631262 | 0.82 | SLC6A3 (0.43) | SLC6A3MEN1KMT2AKDM4CSLC6A2 | |
| SCHEMBL8352398 | 0.76 | SLC6A3 (0.45) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL8592687 | 0.76 | SLC6A3 (0.45) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL3466586 | 0.75 | L3MBTL1 (0.38) | SLC6A3MEN1KMT2AKDM4CSLC6A2 | |
| SCHEMBL8556420 | 0.75 | MEN1 (0.41) | SLC6A3MEN1KMT2AKDM4CKCNA5 | |
| SCHEMBL8706751 | 0.74 | SLC6A3 (0.48) | SLC6A3MEN1KMT2AKDM4CSLC6A2 | |
| SCHEMBL8352404 | 0.73 | SLC6A3 (0.44) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7496624 | 0.73 | SLC6A3 (0.50) | SLC6A3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL8558548 | 0.73 | SLC6A3 (0.41) | SLC6A3MEN1KMT2AKDM4CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591040-B1 | Quaternary basic amides as tachykinines antagonists | SANOFI SA (FR) | 1999-02-03 | — | — | EP | disclosed |
| EP-0591040-A1 | Quaternary basic amides as tachykinines antagonists | SANOFI (FR) | 1994-04-06 | — | — | EP | disclosed |