Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316194 | 0.88 | ALDH1A1 (0.33) | L3MBTL1AKR1B1KMT2AHTTGAA | |
| SCHEMBL8314877 | 0.87 | MEN1 (0.36) | AKR1B1KMT2AHTTGAAMEN1 | |
| SCHEMBL8312522 | 0.82 | ALDH1A1 (0.36) | L3MBTL1AKR1B1KMT2AHTTMEN1 | |
| SCHEMBL8315152 | 0.80 | EGFR (0.30) | AKR1B1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8313666 | 0.77 | TBXA2R (0.31) | AKR1B1KMT2AMEN1ALDH1A1NR3C1 | |
| SCHEMBL8313587 | 0.76 | L3MBTL1 (0.41) | L3MBTL1AKR1B1KMT2AHTTHKDC1 | |
| SCHEMBL8314879 | 0.76 | MEN1 (0.36) | AKR1B1KMT2AHTTGAAMEN1 | |
| SCHEMBL8794145 | 0.74 | TP53 (0.38) | L3MBTL1AKR1B1KMT2AHTTALDH1A1 | |
| SCHEMBL8315687 | 0.74 | AKR1B1 (0.41) | AKR1B1KMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL8314382 | 0.73 | AKR1B1 (0.37) | AKR1B1KMT2AGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |