Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8793993 | 0.85 | EGFR (0.34) | EGFRAKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL8313666 | 0.82 | TBXA2R (0.31) | EGFRAKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL8794707 | 0.81 | NR3C1 (0.32) | EGFRAKR1B1ALDH1A1 | |
| SCHEMBL8316461 | 0.80 | L3MBTL1 (0.41) | AKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL8314196 | 0.80 | TLR3 (0.34) | EGFRAKR1B1ALDH1A1 | |
| SCHEMBL8316194 | 0.79 | ALDH1A1 (0.33) | AKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL8314877 | 0.76 | MEN1 (0.36) | AKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL8312522 | 0.75 | ALDH1A1 (0.36) | AKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL8795239 | 0.73 | GAA (0.36) | AKR1B1ALDH1A1MEN1KMT2A | |
| SCHEMBL29442980 | 0.70 | EGFR (0.34) | EGFRAKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |