Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PYGL | P06737 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319329 | 0.93 | RAB9A (0.53) | HDAC1HDAC8HDAC6HPGDALOX15 | |
| SCHEMBL8318097 | 0.90 | CYP1A2 (0.55) | HDAC1HDAC8HDAC6HPGDKMT2A | |
| SCHEMBL8317818 | 0.89 | HDAC1 (0.51) | HDAC1HDAC8HDAC6HPGDPYGL | |
| SCHEMBL8319324 | 0.86 | RAB9A (0.64) | HDAC1HDAC8HDAC6HPGDPYGL | |
| SCHEMBL8311983 | 0.84 | RAB9A (0.58) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL8318235 | 0.83 | LMNA (0.51) | HPGDALOX15PYGLKMT2AMEN1 | |
| SCHEMBL7334998 | 0.83 | ALDH1A1 (0.65) | HPGDKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL8816442 | 0.82 | RAB9A (0.62) | HPGDKMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL8317200 | 0.82 | RAB9A (0.54) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL8316866 | 0.81 | RAB9A (0.56) | HPGDKMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |