Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253379 | 0.93 | SETD7 (0.57) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8314768 | 0.88 | OPRM1 (0.47) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8314872 | 0.88 | OPRD1 (0.55) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8316991 | 0.88 | OPRM1 (0.52) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8316492 | 0.84 | OPRD1 (0.49) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8317597 | 0.84 | OPRM1 (0.49) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8312303 | 0.84 | OPRD1 (0.55) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8316856 | 0.84 | OPRM1 (0.52) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL9238863 | 0.84 | SETD7 (0.61) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8315369 | 0.83 | MEN1 (0.44) | OPRD1OPRM1OPRK1P2RX7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| CN-1033327-C | Process for preparing tricyclotriazolo derivatives and their use | TORAY INDUSTRIES (JP) | 1996-11-20 | — | — | CN | disclosed |
| CN-1066849-A | Three ring triazolo derivatives, its Manufacturing approach and use | TORAY INDUSTRIES (JP) | 1992-12-09 | — | — | CN | disclosed |