Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315369 | 0.96 | MEN1 (0.44) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL9253379 | 0.89 | SETD7 (0.57) | OPRM1OPRD1OPRK1SETD7P2RX7 | |
| SCHEMBL8316876 | 0.88 | OPRD1 (0.53) | OPRM1OPRD1OPRK1SETD7MEN1 | |
| SCHEMBL8317082 | 0.86 | OPRD1 (0.49) | OPRM1OPRD1OPRK1SETD7P2RX7 | |
| SCHEMBL8317597 | 0.84 | OPRM1 (0.49) | OPRM1OPRD1OPRK1SETD7P2RX7 | |
| SCHEMBL8312626 | 0.83 | DRD4 (0.47) | OPRM1OPRD1OPRK1SETD7KMT2A | |
| SCHEMBL8316991 | 0.82 | OPRM1 (0.52) | OPRM1OPRD1OPRK1SETD7P2RX7 | |
| SCHEMBL8314872 | 0.82 | OPRD1 (0.55) | OPRM1OPRD1OPRK1SETD7P2RX7 | |
| SCHEMBL9238863 | 0.80 | SETD7 (0.61) | OPRM1OPRD1OPRK1SETD7MEN1 | |
| SCHEMBL8315432 | 0.80 | OPRM1 (0.48) | OPRM1OPRD1OPRK1SETD7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| CN-1033327-C | Process for preparing tricyclotriazolo derivatives and their use | TORAY INDUSTRIES (JP) | 1996-11-20 | — | — | CN | disclosed |
| CN-1066849-A | Three ring triazolo derivatives, its Manufacturing approach and use | TORAY INDUSTRIES (JP) | 1992-12-09 | — | — | CN | disclosed |