Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314768 | 0.96 | OPRM1 (0.47) | MEN1KMT2AKCNH2HRH3OPRM1 | |
| SCHEMBL9253379 | 0.84 | SETD7 (0.57) | KCNH2OPRM1OPRD1OPRK1LMNA | |
| SCHEMBL8316876 | 0.83 | OPRD1 (0.53) | MEN1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL8317082 | 0.82 | OPRD1 (0.49) | KCNH2OPRM1OPRD1OPRK1P2RX7 | |
| SCHEMBL8317597 | 0.79 | OPRM1 (0.49) | HRH3OPRM1OPRD1OPRK1P2RX7 | |
| SCHEMBL8312626 | 0.79 | DRD4 (0.47) | KMT2AOPRM1OPRD1OPRK1DRD2 | |
| SCHEMBL8314872 | 0.77 | OPRD1 (0.55) | KCNH2OPRM1OPRD1OPRK1P2RX7 | |
| SCHEMBL8316991 | 0.77 | OPRM1 (0.52) | OPRM1OPRD1OPRK1LMNAP2RX7 | |
| SCHEMBL8315004 | 0.75 | OPRD1 (0.47) | KCNH2OPRM1OPRD1OPRK1P2RX7 | |
| SCHEMBL8315432 | 0.75 | OPRM1 (0.48) | MEN1KMT2AOPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |