Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316992 | 0.89 | HRH3 (0.39) | HRH3HTR1AHTR7DRD2HTR2A | |
| SCHEMBL8314770 | 0.87 | CHRM1 (0.40) | HRH3HTR1AHTR7HRH1 | |
| SCHEMBL8312305 | 0.86 | MC4R (0.39) | HRH3CNR1 | |
| SCHEMBL8316497 | 0.86 | MC4R (0.39) | HRH3DRD2DRD3CNR1MEN1 | |
| SCHEMBL8316861 | 0.86 | HRH3 (0.48) | HRH3HTR1AHTR7 | |
| SCHEMBL8317603 | 0.84 | HRH3 (0.40) | HRH3SIGMAR1DRD3 | |
| SCHEMBL8315438 | 0.81 | KCNH2 (0.43) | HRH3SIGMAR1DRD2DRD3 | |
| SCHEMBL9053675 | 0.80 | PARP1 (0.38) | SIGMAR1HTR1AHTR7DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL11034941 | 0.79 | HRH1 (0.53) | HTR1AHTR7DRD2HTR2AHTR2C | |
| SCHEMBL11287903 | 0.79 | HRH1 (0.42) | HTR1AHTR7DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |