Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054642 | 0.97 | SIGMAR1 (0.39) | PARP1MC4RDRD2DRD4DRD3 | |
| SCHEMBL9054797 | 0.83 | HTR7 (0.47) | MC4RDRD2DRD4DRD3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9055470 | 0.82 | HTR7 (0.46) | MC4RDRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL8316880 | 0.80 | HRH3 (0.39) | DRD2DRD3SIGMAR1HTR1AHTR7 | |
| SCHEMBL9055689 | 0.76 | CARM1 (0.48) | PARP1MC4RDRD2DRD4DRD3 | |
| SCHEMBL9053857 | 0.74 | CARM1 (0.48) | PARP1MC4RDRD2DRD4DRD3 | |
| SCHEMBL9053666 | 0.73 | OPRM1 (0.43) | PARP1DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL9054788 | 0.71 | DRD3 (0.55) | DRD2DRD4DRD3HTR1AHTR7 | |
| SCHEMBL9054632 | 0.71 | OPRM1 (0.43) | DRD2DRD4DRD3SIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL9055462 | 0.70 | DRD3 (0.54) | DRD2DRD4DRD3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706522-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001350-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |