Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312887 | 0.75 | PNMT (0.40) | DPP7ALDH1A1 | |
| SCHEMBL6984270 | 0.74 | ALDH1A1 (0.42) | ALDH1A1BRD4CA1CA2ACACB | |
| SCHEMBL22326600 | 0.70 | TDP2 (0.41) | HRH4TDP2CA1CA2 | |
| SCHEMBL11644407 | 0.68 | KDM4E (0.59) | HRH4ALDH1A1TDP2HTR2AHTR2C | |
| SCHEMBL27394981 | 0.67 | BRD4 (0.62) | BRD4 | |
| SCHEMBL13938028 | 0.65 | TMEM97 (0.54) | DPP7HSD17B3ALDH1A1NOTUMTDP2 | |
| SCHEMBL8317166 | 0.65 | KDM4E (0.39) | DPP7NOTUMTMEM97SIGMAR1KCNH2 | |
| SCHEMBL23745228 | 0.63 | DPP7 (0.68) | DPP7NOTUMACACBTMEM97SIGMAR1 | |
| SCHEMBL2056192 | 0.62 | DPP7 (0.47) | DPP7ALDH1A1NOTUMTDP2TMEM97 | |
| SCHEMBL11484538 | 0.61 | TDP2 (0.42) | BRD4TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929072-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |
| EP-0897921-A1 | Benzothiadiazinyl-indole derivatives and their use as serotonin receptor ligands | ELI LILLY AND COMPANY LIMITED (GB) | 1999-02-24 | — | — | EP | disclosed |