Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.56 |
| ▸ | WNT3A | P56704 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322382 | 0.93 | RAB9A (0.53) | CTNNB1WNT3ANPC1KLF5PKM | |
| SCHEMBL26115654 | 0.78 | KDM4E (0.68) | CTNNB1WNT3ANPC1KLF5PKM | |
| SCHEMBL3787714 | 0.75 | HPGD (0.54) | CTNNB1WNT3ANPC1KLF5PKM | |
| SCHEMBL3788073 | 0.75 | CTNNB1 (0.53) | CTNNB1WNT3ANPC1KLF5PKM | |
| SCHEMBL28860886 | 0.75 | CTNNB1 (0.60) | CTNNB1WNT3ANPC1RAB9ACACNA1H | |
| SCHEMBL26560375 | 0.74 | CTNNB1 (0.42) | CTNNB1WNT3ANPC1KLF5PKM | |
| SCHEMBL1922938 | 0.73 | TAS1R3 (0.59) | NPC1RAB9AHPGDHSD17B10KDM4E | |
| SCHEMBL8891147 | 0.73 | SMN1; SMN2 (0.65) | NPC1RAB9AHPGDKMT2A | |
| SCHEMBL3787786 | 0.73 | TAS1R3 (0.61) | CTNNB1WNT3ANPC1RAB9ACACNA1H | |
| SCHEMBL30572064 | 0.73 | RAB9A (0.53) | CTNNB1WNT3ANPC1RAB9ACACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | claimed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | claimed |