Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 5/20 | 0.42 |
| ▸ | WNT3A | P56704 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317337 | 0.74 | CTNNB1 (0.56) | CTNNB1WNT3ARAB9ANPC1KLF5 | |
| SCHEMBL26115654 | 0.71 | KDM4E (0.68) | CTNNB1WNT3ARAB9ANPC1TP53 | |
| SCHEMBL30571714 | 0.71 | CTNNB1 (0.44) | CTNNB1WNT3ARAB9ANPC1TP53 | |
| SCHEMBL3787786 | 0.69 | TAS1R3 (0.61) | CTNNB1WNT3ARAB9ANPC1TAS1R3 | |
| SCHEMBL3788073 | 0.68 | CTNNB1 (0.53) | CTNNB1WNT3ARAB9ANPC1KLF5 | |
| SCHEMBL30572064 | 0.68 | RAB9A (0.53) | CTNNB1WNT3ARAB9ANPC1TP53 | |
| SCHEMBL8322382 | 0.68 | RAB9A (0.53) | CTNNB1WNT3ARAB9ANPC1KLF5 | |
| SCHEMBL3787714 | 0.66 | HPGD (0.54) | CTNNB1WNT3ARAB9ANPC1KLF5 | |
| SCHEMBL7439487 | 0.66 | KMT2A (0.53) | CTNNB1WNT3ARAB9ANPC1HPGD | |
| SCHEMBL4848144 | 0.66 | CTNNB1 (0.56) | CTNNB1WNT3ARAB9ANPC1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |