SCHEMBL8317351

SCHEMBL8317351

CCOC(C)Oc1cccc(S(OS(C)(=O)=O)(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADAMTS4 O75173 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP13 P45452 1/20 0.32
PGR P06401 1/20 0.32
MMP3 P08254 1/20 0.32
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ESR1 P03372 1/20 0.31
MAPT P10636 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
BCL2L1 Q07817 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8320382 0.89 KAT6A (0.39) ALDH1A1LMNASMN1; SMN2KAT6A
SCHEMBL8322202 0.80 MAPT (0.38) CA12CA2CA9ALDH1A1GAA
SCHEMBL8323445 0.79 PGR (0.34) PGRCA12CA2CA9ALDH1A1
SCHEMBL6140497 0.77 CNR2 (0.35) CA12CA2CA9ALDH1A1GAA
SCHEMBL6140966 0.77 CNR2 (0.35) CA12CA2CA9ALDH1A1GAA
SCHEMBL8320968 0.77 PGR (0.36) PGRCA12CA2CA9ALDH1A1
SCHEMBL8317002 0.77 PGR (0.36) PGRCA12CA2CA9ALDH1A1
SCHEMBL8317348 0.76 ALDH1A1 (0.32) ADAMTS4MMP2MMP9MMP8MMP13
SCHEMBL6140711 0.76 ALDH1A1 (0.38) ALDH1A1LMNAHTTMAPTTDP1
SCHEMBL6140183 0.76 ALDH1A1 (0.38) ALDH1A1LMNAHTTMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880169-A HAVING HIGH RESOLUTION FOR FINE PATTERNING SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-03-09 US disclosed