SCHEMBL8323445

SCHEMBL8323445

CC[Si](CC)(CC)Oc1cccc(S(OS(C)(=O)=O)(c2ccc(N(C)C)cc2)c2ccc(N(C)C)cc2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 3/20 0.34
CA2 P00918 3/20 0.33
CA12 O43570 2/20 0.33
CA9 Q16790 2/20 0.33
LMNA P02545 2/20 0.33
ESR1 P03372 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP11B1 P15538 2/20 0.32
CYP11B2 P19099 1/20 0.32
CA1 P00915 2/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM1A O60341 1/20 0.31
CA4 P22748 1/20 0.31
TERT O14746 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8318578 0.88 ALDH1A1 (0.36) CA2CA12CA9LMNAMAPT
SCHEMBL8320968 0.80 PGR (0.36) PGRCA2CA12CA9LMNA
SCHEMBL8317002 0.80 PGR (0.36) PGRCA2CA12CA9LMNA
SCHEMBL8317351 0.79 ADAMTS4 (0.32) PGRCA2CA12CA9LMNA
SCHEMBL8647451 0.74 KMT2A (0.38) PGRALDH1A1HSD17B10SMN1; SMN2
SCHEMBL8323442 0.74 ESR1 (0.31) ESR1
SCHEMBL8321680 0.74 ELANE (0.36) PGRCA2CA12CA9MAPT
SCHEMBL8325533 0.74 ELANE (0.36) PGRCA2CA12CA9MAPT
SCHEMBL8318999 0.74 PSEN1 (0.39) CA2CA12CA9MAPTCA1
SCHEMBL8323051 0.74 DDB1 (0.35) PGRLMNAMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880169-A HAVING HIGH RESOLUTION FOR FINE PATTERNING SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-03-09 US disclosed