Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322250 | 0.83 | ALDH1A1 (0.53) | SNCAMAPTKMT2ANPC1RAB9A | |
| SCHEMBL8321364 | 0.83 | MAPT (0.50) | SNCAMAPTKMT2ANPC1RAB9A | |
| SCHEMBL8317458 | 0.80 | PKM (0.49) | SNCAMAPTKMT2ANPC1RAB9A | |
| SCHEMBL8314608 | 0.74 | ALDH1A1 (0.55) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15087635 | 0.73 | CNR2 (0.71) | SNCAMAPTKMT2ANPC1RAB9A | |
| SCHEMBL10457551 | 0.72 | ALOX5 (0.67) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8993860 | 0.72 | ALOX5 (0.67) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3448404 | 0.72 | MAPT (0.88) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4582427 | 0.72 | MAPT (0.88) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3448406 | 0.72 | MAPT (0.88) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |