Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313475 | 0.88 | ALDH1A1 (0.48) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8317462 | 0.82 | KMT2A (0.40) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8317404 | 0.80 | SNCA (0.49) | PKMMAPTKMT2ANPC1RAB9A | |
| SCHEMBL8322250 | 0.79 | ALDH1A1 (0.53) | PKMMAPTKMT2ANPC1RAB9A | |
| SCHEMBL8314600 | 0.79 | PKM (0.58) | PKMNPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8320373 | 0.77 | HDAC1 (0.57) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8321364 | 0.77 | MAPT (0.50) | PKMMAPTKMT2ANPC1RAB9A | |
| SCHEMBL8318925 | 0.76 | HDAC1 (0.53) | L3MBTL1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8322075 | 0.76 | RXRA (0.46) | PKMMAPTKMT2AALDH1A1HPGDS | |
| SCHEMBL8314608 | 0.75 | ALDH1A1 (0.55) | MAPTKMT2ANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |