Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 3/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312292 | 0.82 | PDPK1 (0.48) | ALDH1A1TSHRPDPK1PPARGPPARA | |
| SCHEMBL1641620 | 0.80 | SLC6A2 (0.48) | ALDH1A1TSHRACP3SLC6A2SLC6A4 | |
| SCHEMBL8875932 | 0.79 | ALDH1A1 (0.45) | ALDH1A1TSHRPDPK1PPARGPPARA | |
| SCHEMBL3128823 | 0.77 | TAAR1 (0.48) | ALDH1A1PPARGPPARAKIF11PTPN1 | |
| SCHEMBL9733971 | 0.76 | SLC6A9 (0.50) | ALDH1A1TSHRPPARGPPARAKIF11 | |
| SCHEMBL7009003 | 0.76 | SLC6A4 (0.47) | PPARGPPARASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7523008 | 0.75 | ACP3 (0.55) | ALDH1A1TSHRPDPK1KIF11ACP3 | |
| SCHEMBL21085616 | 0.75 | BACE1 (0.47) | ALDH1A1TSHRPPARGPPARAKIF11 | |
| SCHEMBL28604259 | 0.75 | ESR2 (0.51) | ALDH1A1TSHRPDPK1PPARGPPARA | |
| SCHEMBL5755207 | 0.73 | PPARG (0.43) | PPARGPPARAACP3SLC6A9SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929534-A1 | TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS | Takeda Pharmaceutical Company Limited (JP) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998013356-A1 | TRYCYCLIC COMPOUNDS AS PROSTAGLANDIN I2 RECEPTOR AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-02 | — | — | WO | disclosed |