Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178081 | 0.83 | EPHX1 (0.47) | KCNH2TAAR1GABBR2GABBR1ALDH1A1 | |
| SCHEMBL8810284 | 0.82 | GABBR2 (0.53) | SLC6A2SLC6A4SLC6A3TAAR1GABBR2 | |
| SCHEMBL1541691 | 0.82 | GABBR2 (0.53) | SLC6A2SLC6A4SLC6A3TAAR1GABBR2 | |
| SCHEMBL8621230 | 0.82 | GABBR2 (0.53) | SLC6A2SLC6A4SLC6A3TAAR1GABBR2 | |
| SCHEMBL9857073 | 0.81 | SLC6A9 (0.57) | SLC6A9SLC6A2SLC6A4SLC6A3KCNK2 | |
| Hydrochloric Acid SCHEMBL1983404 | 0.80 | GABBR2 (0.52) | SLC6A2SLC6A4SLC6A3TAAR1GABBR2 | |
| SCHEMBL11078290 | 0.78 | TAAR1 (0.48) | SLC6A2SLC6A4SLC6A3KCNK2KCNH2 | |
| SCHEMBL15903897 | 0.77 | ESR1 (0.55) | SLC6A2TAAR1SLC7A5GABBR2GABBR1 | |
| SCHEMBL5308356 | 0.77 | CHRNB2 (0.54) | SLC6A2SLC6A4SLC6A3TAAR1GABBR2 | |
| Hydrochloric Acid SCHEMBL9735324 | 0.77 | CHRNB2 (0.55) | TAAR1GABBR2GABBR1ALDH1A1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5135955-A | Anticoagulants or antifungal activity | ELI LILLY AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0339878-A2 | Propanamine derivatives | ELI LILLY AND COMPANY (US) | 1989-11-02 | — | — | EP | disclosed |