Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.47 |
| ▸ | DRD3 | P35462 | 6/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGAV | P06756 | 5/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8300507 | 0.82 | KDM4E (0.43) | ITGB3ITGA2BTRPV6 | |
| SCHEMBL2843026 | 0.80 | DRD3 (0.56) | DRD2ADRA1ADRD3ITGB3ITGAV | |
| SCHEMBL8304879 | 0.79 | KDM4E (0.42) | DRD2DRD3ITGB3ITGA2BTRPV6 | |
| SCHEMBL8304380 | 0.77 | DRD3 (0.36) | DRD2DRD3TRPV6 | |
| SCHEMBL8300030 | 0.75 | KDM4E (0.45) | DRD2ITGB3ITGA2BTRPV6GRIN2B | |
| Trifluoroacetic Acid SCHEMBL5856786 | 0.74 | DRD2 (0.53) | DRD2ADRA1ADRD3ITGB3ITGAV | |
| SCHEMBL7675724 | 0.74 | DRD2 (0.49) | DRD2ADRA1ADRD3ITGB3ITGAV | |
| SCHEMBL4777735 | 0.74 | CCR3 (0.56) | GRIN2B | |
| SCHEMBL13118499 | 0.73 | DRD2 (0.61) | DRD2ADRA1ADRD3 | |
| SCHEMBL8305139 | 0.73 | CDK9 (0.36) | DRD2TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906103-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-04-07 | — | — | EP | claimed |
| EP-0906103-A4 | — | — | 1999-04-07 | — | — | EP | claimed |
| WO-1997024124-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | claimed |