Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.40 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312303 | 0.95 | OPRD1 (0.55) | OPRD1OPRM1OPRK1SETD7DRD2 | |
| SCHEMBL8315004 | 0.84 | OPRD1 (0.47) | OPRD1OPRM1OPRK1PSMB1PSMB5 | |
| SCHEMBL9253379 | 0.81 | SETD7 (0.57) | OPRD1OPRM1OPRK1PSMB1PSMB5 | |
| SCHEMBL8314872 | 0.80 | OPRD1 (0.55) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL11546026 | 0.79 | OPRD1 (0.57) | OPRD1OPRM1OPRK1DRD2DRD3 | |
| SCHEMBL8316876 | 0.78 | OPRD1 (0.53) | OPRD1OPRM1OPRK1SETD7DRD2 | |
| SCHEMBL11859424 | 0.77 | OPRD1 (0.55) | OPRD1OPRM1OPRK1SETD7DRD2 | |
| SCHEMBL8316991 | 0.77 | OPRM1 (0.52) | OPRD1OPRM1OPRK1SETD7DRD2 | |
| SCHEMBL8316856 | 0.76 | OPRM1 (0.52) | OPRD1OPRM1OPRK1PSMB1PSMB5 | |
| Hydrochloric Acid SCHEMBL11862454 | 0.76 | OPRD1 (0.49) | OPRD1OPRM1OPRK1SETD7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |