Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314872 | 0.94 | OPRD1 (0.55) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL9253379 | 0.84 | SETD7 (0.57) | OPRD1OPRM1OPRK1PSMB1PSMB5 | |
| SCHEMBL8318385 | 0.84 | OPRD1 (0.47) | OPRD1OPRM1OPRK1PSMB1PSMB5 | |
| SCHEMBL8317082 | 0.83 | OPRD1 (0.49) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8316876 | 0.81 | OPRD1 (0.53) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8316991 | 0.80 | OPRM1 (0.52) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8316856 | 0.80 | OPRM1 (0.52) | OPRD1OPRM1OPRK1PSMB1PSMB5 | |
| SCHEMBL8312303 | 0.80 | OPRD1 (0.55) | OPRD1OPRM1OPRK1SETD7P2RX7 | |
| SCHEMBL8317854 | 0.78 | CYP2D6 (0.46) | — | |
| SCHEMBL8311551 | 0.78 | CYP2D6 (0.42) | OPRD1OPRM1OPRK1SETD7P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |