Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065791 | 0.78 | HDAC10 (0.45) | BRD4KDM4ABRD9BAZ2BBAZ2A | |
| SCHEMBL30130815 | 0.78 | GLS (0.45) | BRD4KDM4ABRD9BAZ2BBAZ2A | |
| SCHEMBL23749868 | 0.78 | GLS (0.45) | BRD4KDM4ABRD9BAZ2BBAZ2A | |
| SCHEMBL14367982 | 0.75 | PRMT6 (0.56) | BRD4GLSNAMPTGFERHSD17B10 | |
| SCHEMBL4404243 | 0.75 | LMNA (0.54) | BRD4GLSNAMPTGFERHSD17B10 | |
| SCHEMBL23727979 | 0.74 | BRD4 (0.41) | BRD4KDM4ABRD9BAZ2BBAZ2A | |
| SCHEMBL3838871 | 0.73 | CA12 (0.63) | KDM4ANAMPTL3MBTL1 | |
| SCHEMBL185365 | 0.73 | ATM (0.55) | BRD4KDM4AGLSNAMPTL3MBTL1 | |
| SCHEMBL18664426 | 0.73 | HDAC1 (0.60) | BRD4KDM4AGLSCREBBP | |
| SCHEMBL1111369 | 0.73 | GLS (0.52) | BRD4KDM4AGLSNAMPTCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925296-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011102-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1998-03-19 | — | — | WO | disclosed |