Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320656 | 0.85 | CYP1A2 (0.40) | CYP3A4CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL8324480 | 0.84 | NR4A2 (0.41) | CYP3A4CYP1A2CYP2C19KMT2ANR4A2 | |
| SCHEMBL8323736 | 0.81 | NPSR1 (0.41) | CYP3A4CYP1A2CYP2C19KMT2ANR4A2 | |
| SCHEMBL8318842 | 0.81 | CYP3A4 (0.35) | CYP3A4CYP1A2CYP2C19KMT2ANR4A2 | |
| SCHEMBL8322193 | 0.79 | CYP1A2 (0.37) | CYP3A4CYP1A2CYP2C19KMT2ANR4A2 | |
| SCHEMBL8318303 | 0.77 | TUBB4A (0.39) | CYP3A4CYP1A2CYP2C19KMT2ANR4A2 | |
| SCHEMBL8322152 | 0.76 | LMNA (0.44) | CYP3A4CYP1A2CYP2C19KMT2ANR4A2 | |
| SCHEMBL8318534 | 0.75 | KDM4E (0.46) | CYP3A4CYP1A2CYP2C19KMT2ANR4A2 | |
| SCHEMBL8320338 | 0.75 | RAB9A (0.44) | CYP1A2CYP2C19LMNAALDH1A1GAA | |
| SCHEMBL8324738 | 0.75 | CYP1A2 (0.34) | CYP3A4CYP1A2CYP2C19KMT2ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866594-A | Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-02-02 | — | — | US | disclosed |