Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324480 | 0.90 | NR4A2 (0.41) | RAB9ANPC1LMNAALDH1A1HTT | |
| SCHEMBL8320986 | 0.89 | MAPT (0.46) | RAB9ANPC1MAPTLMNAHPGD | |
| SCHEMBL8322152 | 0.84 | LMNA (0.44) | RAB9ANPC1MAPTLMNAHPGD | |
| SCHEMBL8323736 | 0.81 | NPSR1 (0.41) | RAB9ANPC1MAPTLMNAALDH1A1 | |
| SCHEMBL8322193 | 0.78 | CYP1A2 (0.37) | MAPTLMNAALDH1A1HTTCYP1A2 | |
| SCHEMBL8320679 | 0.78 | LMNA (0.42) | RAB9ANPC1MAPTLMNAALDH1A1 | |
| SCHEMBL8318840 | 0.75 | CYP3A4 (0.35) | RAB9ANPC1MAPTLMNAHPGD | |
| SCHEMBL8318842 | 0.75 | CYP3A4 (0.35) | MAPTLMNAALDH1A1HTTCYP1A2 | |
| SCHEMBL8326166 | 0.75 | ALDH1A1 (0.53) | RAB9ANPC1MAPTLMNAHPGD | |
| SCHEMBL8322185 | 0.74 | MAPT (0.49) | RAB9ANPC1MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866594-A | Indole-2-carboxylate derivatives and fungicidal compositions for agricultural or horticultural use containing the derivatives as active component | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1999-02-02 | — | — | US | disclosed |
| EP-0791582-A1 | INDOLE-2-CARBOXYLIC ESTER DERIVATIVES AND AGRICULTURAL AND HORTICULTURAL BACTERIOCIDES CONTAINING THE SAME AS THE ACTIVE INGREDIENT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-08-27 | — | — | EP | disclosed |